OR1Q1

OR1Q1
Identifiers
Aliases	OR1Q1 , HSTPCR106, OR1Q2, OR1Q3, OR9-25, OR9-A, OST226, OST226OR9-A, TPCR106, olfactory receptor family 1 subfamily Q member 1
External IDs	MGI: 3030191 HomoloGene: 17320 GeneCards: OR1Q1
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,614,738 bp [1] End 122,615,682 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 B Start 36,883,839 bp [2] End 36,891,859 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in stromal cell of endometrium Achilles tendon urinary bladder gallbladder myometrium fundus prefrontal cortex sigmoid colon body of stomach esophagus Top expressed in spermatid More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity transmembrane signaling receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process response to stimulus detection of chemical stimulus involved in sensory perception signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 158131 258616 Ensembl ENSG00000165202 ENSMUSG00000055838 UniProt Q15612 Q8VFP4 RefSeq (mRNA) NM_012364 NM_146623 RefSeq (protein) NP_036496 NP_666834 Location (UCSC) Chr 9: 122.61 – 122.62 Mb Chr 2: 36.88 – 36.89 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 1Q1 is a protein that in humans is encoded by the OR1Q1 gene. ^[5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000165202 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000055838 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR1Q1 olfactory receptor, family 1, subfamily Q, member 1".

Further reading

• Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (February 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID   9119360.
• Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (September 2002). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR1Q1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.