OR2C3

OR2C3
Identifiers
Aliases	OR2C3 , OR2C4, OR2C5P, OST742, olfactory receptor family 2 subfamily C member 3
External IDs	HomoloGene: 64884 GeneCards: OR2C3
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 247,524,677 bp [1] End 247,536,440 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in ganglionic eminence gastric mucosa smooth muscle tissue placenta testicle endometrium gallbladder islet of Langerhans myometrium lymph node n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81472 n/a Ensembl ENSG00000196242 n/a UniProt Q8N628 n/a RefSeq (mRNA) NM_198074 n/a RefSeq (protein) NP_932340 n/a Location (UCSC) Chr 1: 247.52 – 247.54 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 2C3 is a protein that in humans is encoded by the OR2C3 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196242 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR2C3 olfactory receptor, family 2, subfamily C, member 3".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.

External links

• OR2C3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.