OR5AK2

OR5AK2
Identifiers
Aliases	OR5AK2 , olfactory receptor family 5 subfamily AK member 2
External IDs	MGI: 3030827 HomoloGene: 79352 GeneCards: OR5AK2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,988,914 bp [1] End 56,989,843 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 85,244,277 bp [2] End 85,245,221 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen skeletal muscle tissue placenta respiratory system lung n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity odorant binding olfactory receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390181 258427 Ensembl ENSG00000181273 ENSMUSG00000075220 UniProt Q8NH90 Q8VF75 RefSeq (mRNA) NM_001005323 NM_146435 RefSeq (protein) NP_001005323 NP_666646 Location (UCSC) Chr 11: 56.99 – 56.99 Mb Chr 2: 85.24 – 85.25 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5AK2 is a protein that in humans is encoded by the OR5AK2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181273 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075220 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5AK2 olfactory receptor, family 5, subfamily AK, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5AK2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.