OR5K2

OR5K2
Identifiers
Aliases	OR5K2 , OR3-9, olfactory receptor family 5 subfamily K member 2
External IDs	MGI: 3030011 HomoloGene: 121500 GeneCards: OR5K2
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q11.2 Start 98,497,681 bp [1] End 98,498,631 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16|16 C1.2 Start 58,691,318 bp [2] End 58,695,131 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in popliteal artery gastric mucosa gastrocnemius muscle left coronary artery ascending aorta right coronary artery smooth muscle tissue tibial nerve Achilles tendon canal of the cervix n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 402135 258998 Ensembl ENSG00000231861 ENSMUSG00000063137 UniProt Q8NHB8 E9Q7W1 RefSeq (mRNA) NM_001004737 NM_146996 RefSeq (protein) NP_001004737 NP_667207 Location (UCSC) Chr 3: 98.5 – 98.5 Mb Chr 16: 58.69 – 58.7 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5K2 is a protein that in humans is encoded by the OR5K2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000231861 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000063137 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5K2 olfactory receptor, family 5, subfamily K, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3". Nature. 440 (7088): 1194–8. Bibcode:2006Natur.440.1194M. doi: 10.1038/nature04728 . PMID   16641997.

External links

• OR5K2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.