OR13C8

OR13C8
Identifiers
Aliases	OR13C8 , OR37H, OR9-10, olfactory receptor family 13 subfamily C member 8
External IDs	MGI: 3030106 HomoloGene: 17409 GeneCards: OR13C8
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q31.1 Start 104,569,168 bp [1] End 104,570,130 bp [1]
Gene location (Mouse) Chr. Chromosome 4 (mouse) [2] Band 4|4 B2 Start 52,910,207 bp [2] End 52,919,178 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in respiratory epithelium peripheral nervous system olfactory epithelium mirror BioGPS More reference expression data
Gene ontology Molecular function olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 138802 258836 Ensembl ENSG00000186943 ENSMUSG00000051593 UniProt Q8NGS7 Q8VGA0 RefSeq (mRNA) NM_001004483 NM_146839 RefSeq (protein) NP_001004483 NP_667050 Location (UCSC) Chr 9: 104.57 – 104.57 Mb Chr 4: 52.91 – 52.92 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 13C8 is a protein that in humans is encoded by the OR13C8 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000186943 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051593 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR13C8 olfactory receptor, family 13, subfamily C, member 8".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.145.6233 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human". Genomics. 82 (3): 355–64. doi:10.1016/S0888-7543(03)00116-2. PMID   12906860.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.

External links

• OR13C8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.