OR51S1

OR51S1
Identifiers
Aliases	OR51S1 , OR11-24, olfactory receptor family 51 subfamily S member 1
External IDs	MGI: 3030405 HomoloGene: 17498 GeneCards: OR51S1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 4,848,237 bp [1] End 4,849,208 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 102,554,297 bp [2] End 102,566,743 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prostate multicellular organism Top expressed in respiratory epithelium olfactory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 119692 259089 Ensembl ENSG00000176922 ENSMUSG00000043310 UniProt Q8NGJ8 E9Q407 RefSeq (mRNA) NM_001004758 NM_147085 RefSeq (protein) NP_001004758 NP_667296 Location (UCSC) Chr 11: 4.85 – 4.85 Mb Chr 7: 102.55 – 102.57 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 51S1 is a protein that in humans is encoded by the OR51S1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000176922 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000043310 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR51S1 olfactory receptor, family 51, subfamily S, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR51S1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.