OR5AS1

OR5AS1
Identifiers
Aliases	OR5AS1 , OR11-168, olfactory receptor family 5 subfamily AS member 1
External IDs	MGI: 3030945 HomoloGene: 74238 GeneCards: OR5AS1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,027,654 bp [1] End 56,038,191 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,979,525 bp [2] End 86,982,968 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) n/a n/a BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219447 258586 Ensembl ENSG00000181785 ENSMUSG00000075158 UniProt Q8N127 Q7TR55 RefSeq (mRNA) NM_001001921 NM_146593 RefSeq (protein) NP_001001921 NP_666804 Location (UCSC) Chr 11: 56.03 – 56.04 Mb Chr 2: 86.98 – 86.98 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5AS1 is a protein that in humans is encoded by the OR5AS1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein–coupled receptors (GPCR) arising from single coding-exon genes.

Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

References

1. GRCh38: Ensembl release 89: ENSG00000181785 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075158 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5AS1 olfactory receptor, family 5, subfamily AS, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5AS1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.