OR5AT1

OR14A16
Identifiers
Aliases	OR14A16 , OR5AT1, olfactory receptor family 14 subfamily A member 16
External IDs	HomoloGene: 128064 GeneCards: OR14A16
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 247,814,660 bp [1] End 247,824,119 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 284532 n/a Ensembl ENSG00000196772 n/a UniProt Q8NHC5 n/a RefSeq (mRNA) NM_001001966 n/a RefSeq (protein) NP_001001966 n/a Location (UCSC) Chr 1: 247.81 – 247.82 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 14A16 is a protein that in humans is encoded by the OR14A16 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196772 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR5AT1 olfactory receptor, family 5, subfamily AT, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5AT1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.