OR8D1

OR8D1
Identifiers
Aliases	OR8D1 , JCG9, OR8D3, OST004, PDJ9J14, olfactory receptor family 8 subfamily D member 1
External IDs	MGI: 3030767 HomoloGene: 79676 GeneCards: OR8D1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.2 Start 124,302,831 bp [1] End 124,315,099 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.1 Start 38,883,609 bp [2] End 38,891,157 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle rectum Top expressed in adrenal gland More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 283159 258433 Ensembl ENSG00000196341 ENSMUSG00000058515 UniProt Q8WZ84 Q9EQA0 RefSeq (mRNA) NM_001002917 NM_146441 RefSeq (protein) NP_001002917 NP_666652 Location (UCSC) Chr 11: 124.3 – 124.32 Mb Chr 9: 38.88 – 38.89 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8D1 is a protein that in humans is encoded by the OR8D1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196341 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058515 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR8D1 olfactory receptor, family 8, subfamily D, member 1".

Further reading

• Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library". Chem. Senses. 26 (9): 1157–66. doi: 10.1093/chemse/26.9.1157 . PMID   11705801.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8D1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.