OR8K1

OR8K1
Identifiers
Aliases	OR8K1 , OR11-182, OR8N1P, olfactory receptor family 8 subfamily K member 1
External IDs	MGI: 3030880 HomoloGene: 17301 GeneCards: OR8K1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,346,039 bp [1] End 56,346,998 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,045,331 bp [2] End 86,049,658 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in cervix canal of the cervix n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390157 258575 Ensembl ENSG00000150261 ENSG00000263328 ENSMUSG00000075197 UniProt Q8NGG5 Q7TR79 RefSeq (mRNA) NM_001002907 NM_146582 RefSeq (protein) NP_001002907 NP_666793 Location (UCSC) Chr 11: 56.35 – 56.35 Mb Chr 2: 86.05 – 86.05 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8K1 is a protein that in humans is encoded by the OR8K1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000263328 GRCh38: Ensembl release 89: ENSG00000150261, ENSG00000263328 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075197 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR8K1 olfactory receptor, family 8, subfamily K, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8K1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.