OR2AP1

OR2AP1
Identifiers
Aliases	OR2AP1 , OR2AP1P, olfactory receptor family 2 subfamily AP member 1
External IDs	MGI: 3030601 HomoloGene: 105186 GeneCards: OR2AP1
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.2 Start 55,572,468 bp [1] End 55,575,612 bp [1]
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • signal transduction • response to stimulus • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	121129	258315
Ensembl	ENSG00000179615	ENSMUSG00000059762
UniProt	Q8NGE2	Q8VG33
RefSeq (mRNA)	NM_001258285	NM_146318
RefSeq (protein)	NP_001245214	NP_666430
Location (UCSC)	Chr 12: 55.57 – 55.58 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2AP1 is a protein that in humans is encoded by the OR2AP1 gene. ^[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000179615 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR2AP1 olfactory receptor, family 2, subfamily AP, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR2AP1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.