OR8G1

OR8G1
Identifiers
Aliases	OR8G1 , HSTPCR25, OR8G1P, TPCR25, olfactory receptor family 8 subfamily G member 1 (gene/pseudogene), olfactory receptor family 8 subfamily G member 1
External IDs	MGI: 3030801 HomoloGene: 115535 GeneCards: OR8G1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.2 Start 124,241,095 bp [1] End 124,254,364 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.1 Start 39,657,545 bp [2] End 39,662,789 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in secondary oocyte multicellular organism organ system reproductive system reproductive organ gonad male reproductive system testicle n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26494 258086 Ensembl ENSG00000197849 ENSMUSG00000055820 UniProt Q15617 Q7TRA6 RefSeq (mRNA) NM_001002905 NM_012379 NM_001011826 RefSeq (protein) NP_001002905 NP_001011826 Location (UCSC) Chr 11: 124.24 – 124.25 Mb Chr 9: 39.66 – 39.66 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 8G1 is a protein that in humans is encoded by the OR8G1 gene. ^{[5] [6]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[6]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000197849 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000055820 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Vanderhaeghen P, Schurmans S, Vassart G, Parmentier M (Apr 1997). "Specific repertoire of olfactory receptor genes in the male germ cells of several mammalian species". Genomics. 39 (3): 239–46. doi:10.1006/geno.1996.4490. PMID   9119360.
6. "Entrez Gene: OR8G1 olfactory receptor, family 8, subfamily G, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR8G1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.