OR5J2

OR5J2
Identifiers
Aliases	OR5J2 , OR11-266, olfactory receptor family 5 subfamily J member 2
External IDs	MGI: 3030886 HomoloGene: 79679 GeneCards: OR5J2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,176,618 bp [1] End 56,177,556 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,122,799 bp [2] End 86,129,577 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in multicellular organism Top expressed in respiratory epithelium peripheral nervous system olfactory epithelium secondary oocyte embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 282775 259012 Ensembl ENSG00000174957 ENSMUSG00000047149 UniProt Q8NH18 Q8VGR8 RefSeq (mRNA) NM_001005492 NM_147010 RefSeq (protein) NP_001005492 NP_667221 Location (UCSC) Chr 11: 56.18 – 56.18 Mb Chr 2: 86.12 – 86.13 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 5J2 is a protein that in humans is encoded by the OR5J2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000174957 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047149 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5J2 olfactory receptor, family 5, subfamily J, member 2".

Further reading

• Parmentier M, Libert F, Schurmans S, et al. (1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID   1370859. S2CID   43926.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5J2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.