OR2D3

OR2D3
Identifiers
Aliases	OR2D3 , OR11-89, olfactory receptor family 2 subfamily D member 3
External IDs	MGI: 3030550 HomoloGene: 121514 GeneCards: OR2D3
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 6,921,002 bp [1] End 6,921,994 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 106,737,534 bp [2] End 106,749,788 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in bone marrow cells corpus callosum reproductive system reproductive organ male reproductive system gonad testicle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 120775 258597 Ensembl ENSG00000178358 ENSMUSG00000073896 UniProt Q8NGH3 n/a RefSeq (mRNA) NM_001004684 NM_146604 RefSeq (protein) NP_001004684 n/a Location (UCSC) Chr 11: 6.92 – 6.92 Mb Chr 7: 106.74 – 106.75 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2D3 is a protein that in humans is encoded by the OR2D3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitters and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000178358 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000073896 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2D3 olfactory receptor, family 2, subfamily D, member 3".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2D3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.