OR6C1

OR6C1
Identifiers
Aliases	OR6C1 , OST267, olfactory receptor family 6 subfamily C member 1
External IDs	MGI: 3030636; HomoloGene: 105151; GeneCards: OR6C1; OMA:OR6C1 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.2 Start 55,314,343 bp [1] End 55,322,364 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D3 Start 129,513,552 bp [2] End 129,524,038 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390321 258934 Ensembl ENSG00000205330 ENSMUSG00000093866 UniProt Q96RD1 Q8VGJ2 RefSeq (mRNA) NM_001005182 NM_146932 RefSeq (protein) NP_001005182 NP_667143 Location (UCSC) Chr 12: 55.31 – 55.32 Mb Chr 10: 129.51 – 129.52 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 6C1 is a protein that in humans is encoded by the OR6C1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000205330 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000093866 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR6C1 olfactory receptor, family 6, subfamily C, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi: 10.1038/nature04569 . PMID   16541075.

External links

• OR6C1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.