OR6Y1

OR6Y1
Identifiers
Aliases	OR6Y1 , OR1-11, OR6Y2, olfactory receptor family 6 subfamily Y member 1
External IDs	MGI: 3030054 HomoloGene: 67062 GeneCards: OR6Y1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.1 Start 158,544,550 bp [1] End 158,554,405 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H3 Start 174,269,648 bp [2] End 174,278,843 bp [2]
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 391112 546747 Ensembl ENSG00000197532 ENSMUSG00000066671 UniProt Q8NGX8 E9Q050 RefSeq (mRNA) NM_001005189 NM_001386050 NM_207694 RefSeq (protein) NP_001005189 NP_997577 Location (UCSC) Chr 1: 158.54 – 158.55 Mb Chr 1: 174.27 – 174.28 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 6Y1 is a protein that in humans is encoded by the OR6Y1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000197532 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000066671 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR6Y1 olfactory receptor, family 6, subfamily Y, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.

External links

• OR6Y1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.