OR52N4

OR52N4
Identifiers
Aliases	OR52N4 , OR11-64, olfactory receptor family 52 subfamily N member 4 (gene/pseudogene), olfactory receptor family 52 subfamily N member 4
External IDs	MGI: 3030492 HomoloGene: 105161 GeneCards: OR52N4
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 5,754,243 bp [1] End 5,755,958 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 104,292,084 bp [2] End 104,296,512 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in spleen right uterine tube lymph node tibial nerve gastric mucosa right coronary artery appendix blood subcutaneous adipose tissue Achilles tendon Top expressed in olfactory epithelium More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390072 259051 Ensembl ENSG00000181074 ENSMUSG00000070421 UniProt Q8NGI2 n/a RefSeq (mRNA) NM_001005175 NM_147049 RefSeq (protein) NP_001005175 n/a Location (UCSC) Chr 11: 5.75 – 5.76 Mb Chr 7: 104.29 – 104.3 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 52N4 is a protein that in humans is encoded by the OR52N4 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181074 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000070421 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR52N4 olfactory receptor, family 52, subfamily N, member 4".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR52N4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.