OR5M10

OR5M10
Identifiers
Aliases	OR5M10 , OR11-207, olfactory receptor family 5 subfamily M member 10
External IDs	MGI: 3030856 HomoloGene: 128086 GeneCards: OR5M10
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,576,774 bp [1] End 56,577,721 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 85,698,938 bp [2] End 85,699,885 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in salivary gland multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390167 258582 Ensembl ENSG00000254834 ENSMUSG00000057761 UniProt Q6IEU7 L7MTT3 RefSeq (mRNA) NM_001004741 NM_146589 RefSeq (protein) NP_001004741 NP_666800 Location (UCSC) Chr 11: 56.58 – 56.58 Mb Chr 2: 85.7 – 85.7 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 5M10 is a protein that in humans is encoded by the OR5M10 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000254834 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000057761 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5M10 olfactory receptor, family 5, subfamily M, member 10".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi: 10.1038/nature04632 . PMID   16554811.

External links

• OR5M10+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.