OR10G8

OR10G8
Identifiers
Aliases	OR10G8 , OR11-274, OR11-282, olfactory receptor family 10 subfamily G member 8
External IDs	HomoloGene: 88421 GeneCards: OR10G8
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.2 Start 124,026,798 bp [1] End 124,030,634 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sural nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219869 n/a Ensembl ENSG00000234560 n/a UniProt Q8NGN5 n/a RefSeq (mRNA) NM_001004464 n/a RefSeq (protein) NP_001004464 n/a Location (UCSC) Chr 11: 124.03 – 124.03 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 10G8 is a protein that in humans is encoded by the OR10G8 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000234560 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR10G8 olfactory receptor, family 10, subfamily G, member 8".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10G8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.