OR2V2

OR2V2
Identifiers
Aliases	OR2V2 , OR2V3, OST713, olfactory receptor family 2 subfamily V member 2
External IDs	MGI: 3031230; HomoloGene: 28537; GeneCards: OR2V2; OMA:OR2V2 - orthologs
Gene location (Human) Chr. Chromosome 5 (human) [1] Band 5q35.3 Start 181,147,586 bp [1] End 181,159,285 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 B1.2 Start 49,000,809 bp [2] End 49,005,701 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right uterine tube Top expressed in adrenal gland human kidney right kidney proximal tubule heart white adipose tissue pancreas islet of Langerhans quadriceps femoris muscle urinary bladder More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 285659 258334 Ensembl ENSG00000182613 ENSMUSG00000047511 UniProt Q96R30 n/a RefSeq (mRNA) NM_206880 NM_146337 RefSeq (protein) NP_996763 n/a Location (UCSC) Chr 5: 181.15 – 181.16 Mb Chr 11: 49 – 49.01 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2V2 is a protein that in humans is encoded by the OR2V2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000182613 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047511 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2V2 olfactory receptor, family 2, subfamily V, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR2V2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.