OR5H2

OR5H2
Identifiers
Aliases	OR5H2 , OR3-10, olfactory receptor family 5 subfamily H member 2
External IDs	MGI: 3030030 HomoloGene: 74113 GeneCards: OR5H2
Gene location (Human) Chr. Chromosome 3 (human) [1] Band 3q11.2 Start 98,282,505 bp [1] End 98,284,070 bp [1]
Gene location (Mouse) Chr. Chromosome 16 (mouse) [2] Band 16|16 C1.3 Start 58,987,010 bp [2] End 58,990,817 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte ascending aorta n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79310 258775 Ensembl ENSG00000197938 ENSMUSG00000096695 UniProt Q8NGV7 E9PYP4 RefSeq (mRNA) NM_001005482 NM_146779 RefSeq (protein) NP_001005482 NP_666990 Location (UCSC) Chr 3: 98.28 – 98.28 Mb Chr 16: 58.99 – 58.99 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5H2 is a protein that in humans is encoded by the OR5H2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000197938 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000096695 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5H2 olfactory receptor, family 5, subfamily H, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5H2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.