OR4K2

OR4K2
Identifiers
Aliases	OR4K2 , OR14-15, olfactory receptor family 4 subfamily K member 2
External IDs	MGI: 3030564 HomoloGene: 17269 GeneCards: OR4K2
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q11.2 Start 19,875,142 bp [1] End 19,883,932 bp [1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • transmembrane signaling receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • detection of chemical stimulus involved in sensory perception • signal transduction • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	390431	258486
Ensembl	ENSG00000165762	ENSMUSG00000109835
UniProt	Q8NGD2	n/a
RefSeq (mRNA)	NM_001005501	NM_146493
RefSeq (protein)	NP_001005501	n/a
Location (UCSC)	Chr 14: 19.88 – 19.88 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4K2 is a protein that in humans is encoded by the OR4K2 gene. ^[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000165762 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR4K2 olfactory receptor, family 4, subfamily K, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR4K2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.