OR1N2

OR1N2
Identifiers
Aliases	OR1N2 , OR9-23, olfactory receptor family 1 subfamily N member 2
External IDs	MGI: 3030188 HomoloGene: 17443 GeneCards: OR1N2
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,553,112 bp [1] End 122,555,173 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 B Start 36,795,692 bp [2] End 36,806,050 bp [2]
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 138882 258941 Ensembl ENSG00000171501 ENSMUSG00000055088 UniProt Q8NGR9 Q8VGJ8 RefSeq (mRNA) NM_001004457 NM_146939 RefSeq (protein) NP_001004457 NP_667150 Location (UCSC) Chr 9: 122.55 – 122.56 Mb Chr 2: 36.8 – 36.81 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 1N2 is a protein that in humans is encoded by the OR1N2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000171501 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000055088 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR1N2 olfactory receptor, family 1, subfamily N, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR1N2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.