OR5B3

OR5B3
Identifiers
Aliases	OR5B3 , OR11-239, OR5B13, OST129, olfactory receptor family 5 subfamily B member 3
External IDs	MGI: 3031297 HomoloGene: 133886 GeneCards: OR5B3
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 58,402,464 bp [1] End 58,406,874 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 13,208,692 bp [2] End 13,213,764 bp [2]
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 441608 258120 Ensembl ENSG00000172769 ENSMUSG00000096365 UniProt Q8NH48 Q7TQR3 RefSeq (mRNA) NM_001005469 NM_001011840 RefSeq (protein) NP_001005469 NP_001011840 Location (UCSC) Chr 11: 58.4 – 58.41 Mb Chr 19: 13.21 – 13.21 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 5B3 is a protein that in humans is encoded by the OR5B3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G-protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172769 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000096365 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5B3 olfactory receptor, family 5, subfamily B, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5B3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.