OR52E4

OR52E4
Identifiers
Aliases	OR52E4 , OR11-55, olfactory receptor family 52 subfamily E member 4
External IDs	MGI: 3030511 HomoloGene: 81596 GeneCards: OR52E4
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 5,880,629 bp [1] End 5,887,079 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 104,700,579 bp [2] End 104,708,213 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in placenta reproductive organ male reproductive system gonad testicle n/a More reference expression data BioGPS n/a
Gene ontology Molecular function signal transducer activity olfactory receptor activity G protein-coupled receptor activity Cellular component membrane integral component of membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390081 258355 Ensembl ENSG00000180974 ENSMUSG00000073914 UniProt Q8NGH9 Q8VF06 RefSeq (mRNA) NM_001005165 NM_146358 RefSeq (protein) NP_001005165 NP_666470 Location (UCSC) Chr 11: 5.88 – 5.89 Mb Chr 7: 104.7 – 104.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 52E4 is a protein that in humans is encoded by the OR52E4 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000180974 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000073914 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR52E4 olfactory receptor, family 52, subfamily E, member 4".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR52E4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.