OR5T3

OR5T3
Identifiers
Aliases	OR5T3 , OR11-178, OR5T3Q, olfactory receptor family 5 subfamily T member 3
External IDs	MGI: 3030927 HomoloGene: 133610 GeneCards: OR5T3
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,252,254 bp [1] End 56,253,222 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,612,823 bp [2] End 86,617,960 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) n/a n/a BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity neurotransmitter receptor activity G protein-coupled serotonin receptor activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane dendrite Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled serotonin receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390154 258363 Ensembl ENSG00000172489 ENSG00000261897 ENSMUSG00000047969 UniProt Q8NGG3 Q8VF14 RefSeq (mRNA) NM_001004747 NM_146366 NM_001368206 RefSeq (protein) NP_001004747 NP_666478 NP_001355135 Location (UCSC) Chr 11: 56.25 – 56.25 Mb Chr 2: 86.61 – 86.62 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5T3 is a protein that in humans is encoded by the OR5T3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000261897 GRCh38: Ensembl release 89: ENSG00000172489, ENSG00000261897 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000047969 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5T3 olfactory receptor, family 5, subfamily T, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5T3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.