OR5B2

OR5B2
Identifiers
Aliases	OR5B2 , OR11-240, OST073, olfactory receptor family 5 subfamily B member 2
External IDs	HomoloGene: 133897 GeneCards: OR5B2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 58,421,238 bp [1] End 58,428,121 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in coronary artery left coronary artery human musculoskeletal system muscle of leg n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390190 n/a Ensembl ENSG00000172365 n/a UniProt Q96R09 n/a RefSeq (mRNA) NM_001005566 n/a RefSeq (protein) NP_001005566 n/a Location (UCSC) Chr 11: 58.42 – 58.43 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 5B2 is a protein that in humans is encoded by the OR5B2 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172365 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR5B2 olfactory receptor, family 5, subfamily B, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5B2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.