OR52E8

OR52E8
Identifiers
Aliases	OR52E8 , OR11-54, olfactory receptor family 52 subfamily E member 8
External IDs	MGI: 3030509 HomoloGene: 133595 GeneCards: OR52E8
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 5,856,749 bp [1] End 5,857,690 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 104,670,577 bp [2] End 104,677,667 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex brain cerebral cortex multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process response to stimulus signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390079 258147 Ensembl ENSG00000183269 ENSMUSG00000096773 UniProt Q6IFG1 n/a RefSeq (mRNA) NM_001005168 NM_001011848 RefSeq (protein) NP_001005168 n/a Location (UCSC) Chr 11: 5.86 – 5.86 Mb Chr 7: 104.67 – 104.68 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 52E8 is a protein that in humans is encoded by the OR52E8 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000183269 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000096773 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR52E8 olfactory receptor, family 52, subfamily E, member 8".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi: 10.1038/nature04632 . PMID   16554811.

External links

• OR52E8+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.