OR1L3

OR1L3
Identifiers
Aliases	OR1L3 , OR9-28, OR9-D, olfactory receptor family 1 subfamily L member 3
External IDs	HomoloGene: 105279 GeneCards: OR1L3
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,675,130 bp [1] End 122,676,104 bp [1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon lung esophagus brain muscle of leg multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26735 n/a Ensembl ENSG00000171481 n/a UniProt Q8NH93 n/a RefSeq (mRNA) NM_001005234 n/a RefSeq (protein) NP_001005234 n/a Location (UCSC) Chr 9: 122.68 – 122.68 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 1L3 is a protein that in humans is encoded by the OR1L3 gene. ^[3]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[3]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000171481 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Entrez Gene: OR1L3 olfactory receptor, family 1, subfamily L, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.

External links

• OR1L3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.