OR4D11

OR4D11
Identifiers
Aliases	OR4D11 , OR4D11P, olfactory receptor family 4 subfamily D member 11
External IDs	MGI: 3031257 HomoloGene: 128078 GeneCards: OR4D11
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 59,503,576 bp [1] End 59,504,511 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 12,009,151 bp [2] End 12,018,681 bp [2]
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219986 258675 Ensembl ENSG00000176200 ENSMUSG00000067529 UniProt Q8NGI4 Q8VFV0 RefSeq (mRNA) NM_001004706 NM_146680 RefSeq (protein) NP_001004706 NP_666891 Location (UCSC) Chr 11: 59.5 – 59.5 Mb Chr 19: 12.01 – 12.02 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 4D11 is a protein that in humans is encoded by the OR4D11 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000176200 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000067529 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4D11 olfactory receptor, family 4, subfamily D, member 11".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR4D11+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.