OR10P1

OR10P1
Identifiers
Aliases	OR10P1 , OR10P1P, OR10P2P, OR10P3P, OR12-7, OST701, olfactory receptor family 10 subfamily P member 1
External IDs	MGI: 3030630 HomoloGene: 17439 GeneCards: OR10P1
Gene location (Human) Chr. Chromosome 12 (human) [1] Band 12q13.2 Start 55,636,892 bp [1] End 55,637,833 bp [1]
Gene location (Mouse) Chr. Chromosome 10 (mouse) [2] Band 10|10 D3 Start 129,441,361 bp [2] End 129,448,439 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood left ventricle n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 121130 258933 Ensembl ENSG00000175398 ENSMUSG00000052012 UniProt Q8NGE3 Q8VGJ1 RefSeq (mRNA) NM_206899 NM_146931 RefSeq (protein) NP_996782 NP_667142 Location (UCSC) Chr 12: 55.64 – 55.64 Mb Chr 10: 129.44 – 129.45 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10P1 is a protein that in humans is encoded by the OR10P1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000175398 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000052012 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10P1 olfactory receptor, family 10, subfamily P, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. Bibcode:2006Natur.440..346S. doi: 10.1038/nature04569 . PMID   16541075.

External links

• OR10P1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.