OR1J1

OR1J1
Identifiers
Aliases	OR1J1 , OR9-18, hg32, olfactory receptor family 1 subfamily J member 1
External IDs	MGI: 102697 HomoloGene: 66579 GeneCards: OR1J1
Gene location (Human) Chr. Chromosome 9 (human) [1] Band 9q33.2 Start 122,476,958 bp [1] End 122,477,926 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 B Start 36,701,504 bp [2] End 36,707,044 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endometrium gastric mucosa right lung gallbladder upper lobe of left lung male reproductive system testicle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 347168 18328 Ensembl ENSG00000136834 ENSMUSG00000075384 UniProt Q8NGS3 Q60879 RefSeq (mRNA) NM_001004451 NM_206903 RefSeq (protein) NP_001004451 NP_996786 Location (UCSC) Chr 9: 122.48 – 122.48 Mb Chr 2: 36.7 – 36.71 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 1J1 is a protein that in humans is encoded by the OR1J1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000136834 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075384 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR1J1 olfactory receptor, family 1, subfamily J, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.145.6233 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. Bibcode:2004Natur.429..369H. doi:10.1038/nature02465. PMC   2734081 . PMID   15164053.

External links

• OR1J1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.