OR11L1

OR11L1
Identifiers
Aliases	OR11L1 , olfactory receptor family 11 subfamily L member 1
External IDs	MGI: 3030157 HomoloGene: 64865 GeneCards: OR11L1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 247,840,928 bp [1] End 247,841,896 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 B1.3 Start 58,514,985 bp [2] End 58,521,327 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland Top expressed in spermatid stomach prosencephalon More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity molecular function Cellular component integral component of membrane plasma membrane extracellular exosome membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 391189 258373 Ensembl ENSG00000197591 ENSMUSG00000043880 UniProt Q8NGX0 n/a RefSeq (mRNA) NM_001001959 NM_146376 RefSeq (protein) NP_001001959 n/a Location (UCSC) Chr 1: 247.84 – 247.84 Mb Chr 11: 58.51 – 58.52 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 11L1 is a protein that in humans is encoded by the OR11L1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000197591 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000043880 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR11L1 olfactory receptor, family 11, subfamily L, member 1".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR11L1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.