OR52B4

OR52B4
Identifiers
Aliases	OR52B4 , OR11-3, olfactory receptor family 52 subfamily B member 4 (gene/pseudogene), olfactory receptor family 52 subfamily B member 4
External IDs	MGI: 3030381; HomoloGene: 17493; GeneCards: OR52B4; OMA:OR52B4 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 4,367,263 bp [1] End 4,368,386 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 102,183,956 bp [2] End 102,184,891 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in blood brain multicellular organism n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process G protein-coupled receptor signaling pathway sensory perception of smell cognition signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 143496 259083 Ensembl ENSG00000221996 ENSMUSG00000073979 UniProt Q8NGK2 E9PXN3 RefSeq (mRNA) NM_001005161 NM_147079 RefSeq (protein) NP_001005161 NP_667290 Location (UCSC) Chr 11: 4.37 – 4.37 Mb Chr 7: 102.18 – 102.18 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 52B4 is a protein that in humans is encoded by the OR52B4 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000221996 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000073979 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR52B4 olfactory receptor, family 52, subfamily B, member 4".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–2589. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR52B4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.