OR5P2

OR5P2
Identifiers
Aliases	OR5P2 , JCG3, JCG4, olfactory receptor family 5 subfamily P member 2
External IDs	MGI: 3030336 HomoloGene: 72021 GeneCards: OR5P2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11p15.4 Start 7,795,974 bp [1] End 7,796,942 bp [1]
Gene location (Mouse) Chr. Chromosome 7 (mouse) [2] Band 7|7 E3 Start 108,120,032 bp [2] End 108,124,272 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in skin of abdomen urinary bladder fundus head salivary gland pancreas n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 120065 258734 Ensembl ENSG00000276025 ENSG00000280931 ENSG00000183303 ENSMUSG00000058014 UniProt Q8WZ92 Q8VG09 RefSeq (mRNA) NM_153444 NM_146739 RefSeq (protein) NP_703145 NP_666950 Location (UCSC) Chr 11: 7.8 – 7.8 Mb Chr 7: 108.12 – 108.12 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5P2 is a protein that in humans is encoded by the OR5P2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000280931, ENSG00000183303 GRCh38: Ensembl release 89: ENSG00000276025, ENSG00000280931, ENSG00000183303 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000058014 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5P2 olfactory receptor, family 5, subfamily P, member 2".

Further reading

• Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library". Chem. Senses. 26 (9): 1157–66. doi: 10.1093/chemse/26.9.1157 . PMID   11705801.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

External links

• OR5P2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.