OR5U1

OR14J1
Identifiers
Aliases	OR14J1 , OR5U1, OR6-25, bA150A6.4, hs6M1-28, olfactory receptor family 14 subfamily J member 1
External IDs	MGI: 2177508 HomoloGene: 114633 GeneCards: OR14J1
Gene location (Human) Chr. Chromosome 6 (human) [1] Band 6p22.1 Start 29,301,701 bp [1] End 29,313,017 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B1 Start 38,143,840 bp [2] End 38,149,381 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle Top expressed in epithelium organ system sensory system sensory organ respiratory epithelium structure with developmental contribution from neural crest head nervous system peripheral nervous system face More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 442191 258287 Ensembl ENSG00000204695 ENSMUSG00000050613 UniProt Q9UGF5 Q14AJ9 RefSeq (mRNA) NM_030946 NM_146290 RefSeq (protein) NP_112208 NP_666402 Location (UCSC) Chr 6: 29.3 – 29.31 Mb Chr 17: 38.14 – 38.15 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 14J1 is a protein that in humans is encoded by the OR14J1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000204695 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000050613 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5U1 olfactory receptor, family 5, subfamily U, member 1".

Further reading

• Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6". Nature. 425 (6960): 805–11. Bibcode:2003Natur.425..805M. doi: 10.1038/nature02055 . PMID   14574404.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5U1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.