OR4D9

OR4D9
Identifiers
Aliases	OR4D9 , OR11-253, olfactory receptor family 4 subfamily D member 9
External IDs	MGI: 3031259 HomoloGene: 17398 GeneCards: OR4D9
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 59,511,368 bp [1] End 59,520,703 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 12,050,598 bp [2] End 12,055,095 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in kidney multicellular organism Top expressed in haematopoietic system thymus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity transmembrane signaling receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process response to stimulus detection of chemical stimulus involved in sensory perception signal transduction sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 390199 258155 Ensembl ENSG00000172742 ENSMUSG00000067526 UniProt Q8NGE8 n/a RefSeq (mRNA) NM_001004711 NM_001011853 RefSeq (protein) NP_001004711 n/a Location (UCSC) Chr 11: 59.51 – 59.52 Mb Chr 19: 12.05 – 12.06 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4D9 is a protein that in humans is encoded by the OR4D9 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172742 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000067526 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4D9 olfactory receptor, family 4, subfamily D, member 9".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Taylor TD, Noguchi H, Totoki Y, et al. (2006). "Human chromosome 11 DNA sequence and analysis including novel gene identification". Nature. 440 (7083): 497–500. Bibcode:2006Natur.440..497T. doi: 10.1038/nature04632 . PMID   16554811.

External links

• OR4D9+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.