OR6B3

OR6B3
Identifiers
Aliases	OR6B3 , OR6B3P, OR6B3Q, olfactory receptor family 6 subfamily B member 3
External IDs	MGI: 3031248 HomoloGene: 88368 GeneCards: OR6B3
Gene location (Human) Chr. Chromosome 2 (human) [1] Band 2q37.3 Start 240,045,077 bp [1] End 240,047,027 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 D Start 92,434,088 bp [2] End 92,446,383 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibial nerve sural nerve substantia nigra hippocampus proper prefrontal cortex urinary bladder Brodmann area 9 temporal lobe amygdala telencephalic nucleus n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 150681 259041 Ensembl ENSG00000178586 ENSMUSG00000042849 UniProt Q8NGW1 Q8VGU5 RefSeq (mRNA) NM_173351 NM_147039 RefSeq (protein) NP_775486 NP_667250 Location (UCSC) Chr 2: 240.05 – 240.05 Mb Chr 1: 92.43 – 92.45 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 6B3 is a protein that in humans is encoded by the OR6B3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000178586 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000042849 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR6B3 olfactory receptor, family 6, subfamily B, member 3".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR6B3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.