OR10H3

OR10H3
Identifiers
Aliases	OR10H3 , olfactory receptor family 10 subfamily H member 3
External IDs	MGI: 1335096 HomoloGene: 130665 GeneCards: OR10H3
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.12 Start 15,737,985 bp [1] End 15,742,343 bp [1]
Gene location (Mouse) Chr. Chromosome 17 (mouse) [2] Band 17|17 B1 Start 33,483,650 bp [2] End 33,494,618 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in pancreatic ductal cell tibialis anterior muscle optic nerve fundus n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity neurotransmitter receptor activity G protein-coupled serotonin receptor activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane dendrite Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled serotonin receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26532 258939 Ensembl ENSG00000171936 ENSMUSG00000054666 UniProt O60404 Q8VBW9 RefSeq (mRNA) NM_013938 NM_146937 RefSeq (protein) NP_039226 NP_667148 Location (UCSC) Chr 19: 15.74 – 15.74 Mb Chr 17: 33.48 – 33.49 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10H3 is a protein that in humans is encoded by the OR10H3 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000171936 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000054666 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10H3 olfactory receptor, family 10, subfamily H, member 3".

Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Gevaert K, Goethals M, Martens L, et al. (2004). "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides". Nat. Biotechnol. 21 (5): 566–9. doi:10.1038/nbt810. PMID   12665801. S2CID   23783563.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Grimwood J, Gordon LA, Olsen A, et al. (2004). "The DNA sequence and biology of human chromosome 19". Nature. 428 (6982): 529–35. Bibcode:2004Natur.428..529G. doi: 10.1038/nature02399 . PMID   15057824.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

External links

• OR10H3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.