OR5F1

OR5F1
Identifiers
Aliases	OR5F1 , OR11-10, olfactory receptor family 5 subfamily F member 1
External IDs	OMIM: 608492 HomoloGene: 130524 GeneCards: OR5F1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 55,993,681 bp [1] End 55,994,625 bp [1]
Gene ontology Molecular function G protein-coupled receptor activity odorant binding signal transducer activity olfactory receptor activity Cellular component membrane plasma membrane integral component of membrane Biological process signal transduction response to stimulus sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 338674 n/a Ensembl ENSG00000149133 n/a UniProt O95221 n/a RefSeq (mRNA) NM_003697 n/a RefSeq (protein) NP_003688 n/a Location (UCSC) Chr 11: 55.99 – 55.99 Mb n/a PubMed search [2] n/a
Wikidata
View/Edit Human

Olfactory receptor 5F1 is a protein that in humans is encoded by the OR5F1 gene. ^{[3] [4]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000149133 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Buettner JA, Glusman G, Ben-Arie N, Ramos P, Lancet D, Evans GA (Dec 1998). "Organization and evolution of olfactory receptor genes on human chromosome 11". Genomics. 53 (1): 56–68. doi:10.1006/geno.1998.5422. PMID   9787077.
4. "Entrez Gene: OR5F1 olfactory receptor, family 5, subfamily F, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.135.3652 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5F1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.