OR10X1

OR10X1
Identifiers
Aliases	OR10X1 , OR1-13, OR1-14, OR10X1P, olfactory receptor family 10 subfamily X member 1 (gene/pseudogene), olfactory receptor family 10 subfamily X member 1
External IDs	MGI: 3030251 HomoloGene: 17358 GeneCards: OR10X1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.1 Start 158,578,919 bp [1] End 158,579,899 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H3 Start 174,192,688 bp [2] End 174,202,038 bp [2]
Gene ontology Molecular function olfactory receptor activity signal transducer activity G protein-coupled receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 128367 258238 Ensembl ENSG00000279111 ENSMUSG00000066672 UniProt Q8NGY0 F8VQB1 RefSeq (mRNA) NM_001004477 NM_207137 RefSeq (protein) NP_001004477 NP_997020 Location (UCSC) Chr 1: 158.58 – 158.58 Mb Chr 1: 174.19 – 174.2 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 10X1 is a protein that in humans is encoded by the OR10X1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000279111 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000066672 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10X1 olfactory receptor, family 10, subfamily X, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes" (PDF). Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.

External links

• OR10X1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.