OR5T2

OR5T2
Identifiers
Aliases	OR5T2 , OR11-177, olfactory receptor family 5 subfamily T member 2
External IDs	MGI: 3030920 HomoloGene: 73975 GeneCards: OR5T2
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 56,231,282 bp [1] End 56,234,255 bp [1]
Gene location (Mouse) Chr. Chromosome 2 (mouse) [2] Band 2|2 D Start 86,506,562 bp [2] End 86,510,436 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endometrium n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity neurotransmitter receptor activity G protein-coupled serotonin receptor activity Cellular component integral component of membrane plasma membrane membrane integral component of plasma membrane dendrite Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell signal transduction response to stimulus G protein-coupled serotonin receptor signaling pathway G protein-coupled receptor signaling pathway G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger chemical synaptic transmission Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219464 258585 Ensembl ENSG00000181718 ENSG00000262851 ENSMUSG00000075175 UniProt Q8NGG2 Q8VFL9 RefSeq (mRNA) NM_001004746 NM_146592 RefSeq (protein) NP_001004746 NP_666803 Location (UCSC) Chr 11: 56.23 – 56.23 Mb Chr 2: 86.51 – 86.51 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 5T2 is a protein that in humans is encoded by the OR5T2 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. ENSG00000262851 GRCh38: Ensembl release 89: ENSG00000181718, ENSG00000262851 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000075175 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR5T2 olfactory receptor, family 5, subfamily T, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR5T2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.