OR4D5

OR4D5
Identifiers
Aliases	OR4D5 , OR11-276, olfactory receptor family 4 subfamily D member 5
External IDs	MGI: 3030818 HomoloGene: 17314 GeneCards: OR4D5
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.1 Start 123,939,617 bp [1] End 123,940,573 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.1 Start 40,007,811 bp [2] End 40,025,502 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in body of pancreas rectum n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219875 258601 Ensembl ENSG00000171014 ENSMUSG00000045812 UniProt Q8NGN0 Q8VFN1 RefSeq (mRNA) NM_001001965 NM_146608 RefSeq (protein) NP_001001965 NP_666819 Location (UCSC) Chr 11: 123.94 – 123.94 Mb Chr 9: 40.01 – 40.03 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 4D5 is a protein that in humans is encoded by the OR4D5 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000171014 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000045812 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR4D5 olfactory receptor, family 4, subfamily D, member 5".

Further reading

• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR4D5+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.