OR10G3

OR10G3
Identifiers
Aliases	OR10G3 , olfactory receptor, family 10, subfamily G, member 3, OR14-40, olfactory receptor family 10 subfamily G member 3
External IDs	MGI: 3031346 HomoloGene: 27165 GeneCards: OR10G3
Gene location (Human) Chr. Chromosome 14 (human) [1] Band 14q11.2 Start 21,568,520 bp [1] End 21,580,076 bp [1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	26533	258424
Ensembl	ENSG00000169208	ENSMUSG00000094140
UniProt	Q8NGC4	Q8VF72
RefSeq (mRNA)	NM_001005465	NM_146432
RefSeq (protein)	NP_001005465	NP_666643
Location (UCSC)	Chr 14: 21.57 – 21.58 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10G3 is a protein that in humans is encoded by the OR10G3 gene. ^{[4] [5]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000169208 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Koop BF, Rowen L, Wang K, Kuo CL, Seto D, Lenstra JA, Howard S, Shan W, Deshpande P, Hood L (Jun 1994). "The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA". Genomics. 19 (3): 478–93. doi:10.1006/geno.1994.1097. PMID   8188290.
5. "Entrez Gene: OR10G3 olfactory receptor, family 10, subfamily G, member 3".

Further reading

• Boysen C, Simon MI, Hood L (1997). "Analysis of the 1.1-Mb human alpha/delta T-cell receptor locus with bacterial artificial chromosome clones". Genome Res. 7 (4): 330–8. doi: 10.1101/gr.7.4.330 . PMID   9110172.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR10G3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.