OR10J1

OR10J1
Identifiers
Aliases	OR10J1 , HGMP07J, HSHGMP07J, olfactory receptor family 10 subfamily J member 1
External IDs	MGI: 3030252 HomoloGene: 8218 GeneCards: OR10J1
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q23.2 Start 159,437,845 bp [1] End 159,443,078 bp [1]
Gene location (Mouse) Chr. Chromosome 1 (mouse) [2] Band 1|1 H3 Start 173,093,568 bp [2] End 173,101,561 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in sperm human musculoskeletal system muscular system muscle organ muscle organ muscle of leg lower leg gastrocnemius muscle Top expressed in ileum jejunum More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity transmembrane signaling receptor activity Cellular component integral component of membrane plasma membrane integral component of plasma membrane membrane Biological process sensory perception of chemical stimulus sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction single fertilization response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 26476 258645 Ensembl ENSG00000196184 ENSMUSG00000049605 UniProt P30954 A0A140T8J6 RefSeq (mRNA) NM_012351 NM_001363557 NM_001363558 NM_146651 RefSeq (protein) NP_036483 NP_001350486 NP_001350487 NP_666862 Location (UCSC) Chr 1: 159.44 – 159.44 Mb Chr 1: 173.09 – 173.1 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10J1 is a protein that in humans is encoded by the OR10J1 gene. ^{[5] [6]}

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[6]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196184 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049605 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Parmentier M, Libert F, Schurmans S, Schiffmann S, Lefort A, Eggerickx D, Ledent C, Mollereau C, Gerard C, Perret J, et al. (Mar 1992). "Expression of members of the putative olfactory receptor gene family in mammalian germ cells". Nature. 355 (6359): 453–5. Bibcode:1992Natur.355..453P. doi:10.1038/355453a0. PMID   1370859. S2CID   43926.
6. "Entrez Gene: OR10J1 olfactory receptor, family 10, subfamily J, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi: 10.1073/pnas.242603899 . PMC   139241 . PMID   12477932.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC   528928 . PMID   15489334.

External links

• OR10J1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.