OR10W1

OR10W1
Identifiers
Aliases	OR10W1 , OR10W1P, OR10W1Q, OR11-236, UNQ6469, olfactory receptor family 10 subfamily W member 1
External IDs	MGI: 3031324 HomoloGene: 79418 GeneCards: OR10W1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q12.1 Start 58,266,792 bp [1] End 58,268,260 bp [1]
Gene location (Mouse) Chr. Chromosome 19 (mouse) [2] Band 19|19 A Start 13,628,455 bp [2] End 13,636,909 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) n/a Top expressed in respiratory epithelium olfactory epithelium BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81341 258098 Ensembl ENSG00000172772 ENSMUSG00000061387 UniProt Q8NGF6 n/a RefSeq (mRNA) NM_207374 NM_001011832 RefSeq (protein) NP_997257 n/a Location (UCSC) Chr 11: 58.27 – 58.27 Mb Chr 19: 13.63 – 13.64 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10W1 is a protein that in humans is encoded by the OR10W1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000172772 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000061387 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10W1 olfactory receptor, family 10, subfamily W, member 1".

Further reading

• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC   403697 . PMID   12975309.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10W1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.