OR2Z1

OR2Z1
Identifiers
Aliases	OR2Z1 , OR19-4, OR2Z2, olfactory receptor family 2 subfamily Z member 1
External IDs	MGI: 3030206 HomoloGene: 17287 GeneCards: OR2Z1
Gene location (Human) Chr. Chromosome 19 (human) [1] Band 19p13.2 Start 8,721,634 bp [1] End 8,732,160 bp [1]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G protein-coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • plasma membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	284383	404315
Ensembl	ENSG00000181733	ENSMUSG00000069998
UniProt	Q8NG97	Q7TRY2
RefSeq (mRNA)	NM_001004699	NM_207555
RefSeq (protein)	NP_001004699	NP_997438
Location (UCSC)	Chr 19: 8.72 – 8.73 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 2Z1 is a protein that in humans is encoded by the OR2Z1 gene. ^[4]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000181733 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR2Z1 olfactory receptor, family 2, subfamily Z, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC   356993 . PMID   14983052.

External links

• OR2Z1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.