OR2B11

OR2B11
Identifiers
Aliases	OR2B11 , olfactory receptor family 2 subfamily B member 11
External IDs	MGI: 3030056; HomoloGene: 71979; GeneCards: OR2B11; OMA:OR2B11 - orthologs
Gene location (Human) Chr. Chromosome 1 (human) [1] Band 1q44 Start 247,449,118 bp [1] End 247,458,105 bp [1]
Gene location (Mouse) Chr. Chromosome 11 (mouse) [2] Band 11|11 B1.3 Start 59,461,081 bp [2] End 59,467,061 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in granulocyte monocyte bone marrow blood sural nerve gallbladder appendix placenta ventricular zone lymph node Top expressed in embryo respiratory epithelium nasal epithelium olfactory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity olfactory receptor activity Cellular component plasma membrane membrane integral component of membrane Biological process signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 127623 257962 Ensembl ENSG00000177535 ENSMUSG00000059610 UniProt Q5JQS5 Q7TS30 RefSeq (mRNA) NM_001004492 NM_001011789 RefSeq (protein) NP_001004492 NP_001011789 Location (UCSC) Chr 1: 247.45 – 247.46 Mb Chr 11: 59.46 – 59.47 Mb PubMed search [3] [4]
Wikidata
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Olfactory receptor 2B11 is a protein that in humans is encoded by the OR2B11 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000177535 – Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059610 – Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2B11 olfactory receptor, family 2, subfamily B, member 11".

Further reading

• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. Bibcode:2006Natur.441..315G. doi: 10.1038/nature04727 . PMID   16710414.

External links

• OR2B11+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.