OR10S1

OR10S1
Identifiers
Aliases	OR10S1 , OR11-279, olfactory receptor family 10 subfamily S member 1
External IDs	MGI: 3030816 HomoloGene: 17415 GeneCards: OR10S1
Gene location (Human) Chr. Chromosome 11 (human) [1] Band 11q24.1 Start 123,976,661 bp [1] End 123,977,781 bp [1]
Gene location (Mouse) Chr. Chromosome 9 (mouse) [2] Band 9|9 A5.1 Start 39,985,125 bp [2] End 39,990,700 bp [2]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in endocrine system endocrine gland thyroid gland Top expressed in respiratory epithelium sensory system sensory organ olfactory epithelium More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 219873 258853 Ensembl ENSG00000196248 ENSMUSG00000049010 UniProt Q8NGN2 Q8VGB3 RefSeq (mRNA) NM_001004474 NM_146854 RefSeq (protein) NP_001004474 NP_667065 Location (UCSC) Chr 11: 123.98 – 123.98 Mb Chr 9: 39.99 – 39.99 Mb PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 10S1 is a protein that in humans is encoded by the OR10S1 gene. ^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. ^[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000196248 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049010 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR10S1 olfactory receptor, family 10, subfamily S, member 1".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX   10.1.1.145.6233 . doi:10.1006/geno.2002.6830. PMID   12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi: 10.1073/pnas.0307882100 . PMC   356993 . PMID   14983052.

External links

• OR10S1+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.