TAS2R45

TAS2R45
Identifiers
Aliases	TAS2R45 , GPR59, T2R45, ZG24P, taste 2 receptor member 45
External IDs	OMIM: 613967; GeneCards: TAS2R45; OMA:TAS2R45 - orthologs
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.2 Start 11,182,986 bp End 11,184,006 bp
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 259291 n/a Ensembl ENSG00000261936 n/a UniProt P59539 n/a RefSeq (mRNA) NM_176886 n/a RefSeq (protein) NP_795367 n/a Location (UCSC) Chr 12: 11.18 – 11.18 Mb n/a PubMed search [1] n/a
Wikidata
View/Edit Human

Taste receptor type 2 member 45 is a protein that in humans is encoded by the TAS2R45 gene. ^{[2] [3]}

See also

• Taste receptor

References

1. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
2. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID   12379855. S2CID   20426192.
3. "Entrez Gene: TAS2R45 taste receptor, type 2, member 45".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi: 10.1074/jbc.R100054200 . PMID   11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID   12139982. S2CID   37807140.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi: 10.1016/S0092-8674(03)00071-0 . PMID   12581520. S2CID   718601.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC   1449719 . PMID   15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.